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semiconductor-based influenza a research microarray  (CombiMatrix)

 
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    Structured Review

    CombiMatrix semiconductor-based influenza a research microarray
    Simplified schematic overview of the gold nanoparticle (NP)-based <t>microarray</t> assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.
    Semiconductor Based Influenza A Research Microarray, supplied by CombiMatrix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/semiconductor-based influenza a research microarray/product/CombiMatrix
    Average 90 stars, based on 1 article reviews
    semiconductor-based influenza a research microarray - by Bioz Stars, 2026-04
    90/100 stars

    Images

    1) Product Images from "Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay"

    Article Title: Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay

    Journal: BMC Biotechnology

    doi: 10.1186/1472-6750-10-74

    Simplified schematic overview of the gold nanoparticle (NP)-based microarray assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.
    Figure Legend Snippet: Simplified schematic overview of the gold nanoparticle (NP)-based microarray assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.

    Techniques Used: Microarray, Modification, Silver Staining

    Image from a Verigene ID™ detection system . (A). Microarray layout with positive control capture (closed red circles on the top), negative control which uses printing buffer as capture (closed yellow circles), M, H5, and N1 gene captures (filled as variable color of closed circles, spotted in triplicate) are indicated. (B). The light shades represent strong silver staining signals. A portion of the microarray images for DNA oligonucleotide following hybridization with PCR fragment are shown and light shades represent greater silver intensities for the M and H5 genes. The spots at the top of each array are positive controls. (C). Silver staining image for individual or multiple PCR products are shown and labeled. (D). Typical genomic microarray silver staining image from 0.2 μg of H1N1, H3N2 or H5N1 viral RNA are shown. The boxed areas highlight hits for specific subtypes.
    Figure Legend Snippet: Image from a Verigene ID™ detection system . (A). Microarray layout with positive control capture (closed red circles on the top), negative control which uses printing buffer as capture (closed yellow circles), M, H5, and N1 gene captures (filled as variable color of closed circles, spotted in triplicate) are indicated. (B). The light shades represent strong silver staining signals. A portion of the microarray images for DNA oligonucleotide following hybridization with PCR fragment are shown and light shades represent greater silver intensities for the M and H5 genes. The spots at the top of each array are positive controls. (C). Silver staining image for individual or multiple PCR products are shown and labeled. (D). Typical genomic microarray silver staining image from 0.2 μg of H1N1, H3N2 or H5N1 viral RNA are shown. The boxed areas highlight hits for specific subtypes.

    Techniques Used: Microarray, Positive Control, Negative Control, Silver Staining, Hybridization, Labeling

    Results of genomic array detection of influenza A viruses with specific captures
    Figure Legend Snippet: Results of genomic array detection of influenza A viruses with specific captures

    Techniques Used:



    Similar Products

    semiconductor-based influenza a research microarray  (CombiMatrix)
    90
    CombiMatrix semiconductor-based influenza a research microarray
    Simplified schematic overview of the gold nanoparticle (NP)-based <t>microarray</t> assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.
    Semiconductor Based Influenza A Research Microarray, supplied by CombiMatrix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/semiconductor-based influenza a research microarray/product/CombiMatrix
    Average 90 stars, based on 1 article reviews
    semiconductor-based influenza a research microarray - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier
    semiconductor-based influenza a microarray  (CombiMatrix)
    90
    CombiMatrix semiconductor-based influenza a microarray
    Simplified schematic overview of the gold nanoparticle (NP)-based <t>microarray</t> assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.
    Semiconductor Based Influenza A Microarray, supplied by CombiMatrix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/semiconductor-based influenza a microarray/product/CombiMatrix
    Average 90 stars, based on 1 article reviews
    semiconductor-based influenza a microarray - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Simplified schematic overview of the gold nanoparticle (NP)-based microarray assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.

    Journal: BMC Biotechnology

    Article Title: Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay

    doi: 10.1186/1472-6750-10-74

    Figure Lengend Snippet: Simplified schematic overview of the gold nanoparticle (NP)-based microarray assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.

    Article Snippet: CombiMatrix Corporation has also developed a semiconductor-based Influenza A Research Microarray that can detect all known subtypes of influenza A viruses within 5 hours [ ].

    Techniques: Microarray, Modification, Silver Staining

    Image from a Verigene ID™ detection system . (A). Microarray layout with positive control capture (closed red circles on the top), negative control which uses printing buffer as capture (closed yellow circles), M, H5, and N1 gene captures (filled as variable color of closed circles, spotted in triplicate) are indicated. (B). The light shades represent strong silver staining signals. A portion of the microarray images for DNA oligonucleotide following hybridization with PCR fragment are shown and light shades represent greater silver intensities for the M and H5 genes. The spots at the top of each array are positive controls. (C). Silver staining image for individual or multiple PCR products are shown and labeled. (D). Typical genomic microarray silver staining image from 0.2 μg of H1N1, H3N2 or H5N1 viral RNA are shown. The boxed areas highlight hits for specific subtypes.

    Journal: BMC Biotechnology

    Article Title: Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay

    doi: 10.1186/1472-6750-10-74

    Figure Lengend Snippet: Image from a Verigene ID™ detection system . (A). Microarray layout with positive control capture (closed red circles on the top), negative control which uses printing buffer as capture (closed yellow circles), M, H5, and N1 gene captures (filled as variable color of closed circles, spotted in triplicate) are indicated. (B). The light shades represent strong silver staining signals. A portion of the microarray images for DNA oligonucleotide following hybridization with PCR fragment are shown and light shades represent greater silver intensities for the M and H5 genes. The spots at the top of each array are positive controls. (C). Silver staining image for individual or multiple PCR products are shown and labeled. (D). Typical genomic microarray silver staining image from 0.2 μg of H1N1, H3N2 or H5N1 viral RNA are shown. The boxed areas highlight hits for specific subtypes.

    Article Snippet: CombiMatrix Corporation has also developed a semiconductor-based Influenza A Research Microarray that can detect all known subtypes of influenza A viruses within 5 hours [ ].

    Techniques: Microarray, Positive Control, Negative Control, Silver Staining, Hybridization, Labeling

    Results of genomic array detection of influenza A viruses with specific captures

    Journal: BMC Biotechnology

    Article Title: Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay

    doi: 10.1186/1472-6750-10-74

    Figure Lengend Snippet: Results of genomic array detection of influenza A viruses with specific captures

    Article Snippet: CombiMatrix Corporation has also developed a semiconductor-based Influenza A Research Microarray that can detect all known subtypes of influenza A viruses within 5 hours [ ].

    Techniques: